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Interferon-α (IFNα) signaling is essential for antiviral response via induction of IFN-stimulated genes (ISGs). Through a non-biased high-throughput RNAi screening of 711 known epigenetic modifiers in cellular models of IFNα-mediated inhibition of HBV replication, we identified methyltransferase SETD2 as a critical amplifier of IFNα-mediated antiviral immunity.

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Oxidative stress and neuroinflammation have been deeply associated with Alzheimer''s disease. DL0410 is a novel acetylcholinesterase inhibitor with potential anti-oxidative effects in AD-related animal models, while the specific mechanism has not been fully clarified. In this study, DL0410 was predic …

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2021-8-25 · Do not worry. You are at the right place. Following are the 18 PM Interview questions asked in common and we will guide you on how to answer them one-by-one with example answers. If you wish to assess yourself in a real-like PM interview …

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Scotland stun Bangladesh to make dream start to T20 …

2021-10-17 · First published on Sun 17 Oct 2021 10.24 EDT Chris Greaves was the hero as Scotland got their T20 World Cup campaign off to a dream start with a six-run victory over highly fancied Bangladesh in ...

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